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EON
2008
13 years 10 months ago
Abductive Synthesis of the Mediator Scenario with jABC and GEM
We reuse here the framework, the setting, and the semantic modelling for the automated synthesis of the SWS Challenge Mediator presented in the companion paper [5], and show how to...
Christian Kubczak, Tiziana Margaria, Matthias Kais...
BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2008
116views more  BMCBI 2008»
13 years 9 months ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
BMCBI
2008
132views more  BMCBI 2008»
13 years 9 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2006
202views more  BMCBI 2006»
13 years 8 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...