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BMCBI
2010
109views more  BMCBI 2010»
13 years 9 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
BMCBI
2010
116views more  BMCBI 2010»
13 years 9 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2008
95views more  BMCBI 2008»
13 years 9 months ago
Methodology capture: discriminating between the "best" and the rest of community practice
Background: The methodologies we use both enable and help define our research. However, as experimental complexity has increased the choice of appropriate methodologies has become...
James M. Eales, John W. Pinney, Robert D. Stevens,...
BMCBI
2007
100views more  BMCBI 2007»
13 years 9 months ago
SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)
Background: The need to build a tool to facilitate the quick creation and editing of models encoded in the Systems Biology Markup language (SBML) has been growing with the number ...
Nicolas Rodriguez, Marco Donizelli, Nicolas Le Nov...
BMCBI
2010
164views more  BMCBI 2010»
13 years 9 months ago
Flexible network reconstruction from relational databases with Cytoscape and CytoSQL
Background: Molecular interaction networks can be efficiently studied using network visualization software such as Cytoscape. The relevant nodes, edges and their attributes can be...
Kris Laukens, Jens Hollunder, Thanh Hai Dang, Geer...