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» Genes, Themes, and Microarrays: Using Information Retrieval ...
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BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2006
164views more  BMCBI 2006»
13 years 7 months ago
Evaluation of clustering algorithms for gene expression data
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...
Susmita Datta, Somnath Datta
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
BMCBI
2008
149views more  BMCBI 2008»
13 years 6 months ago
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Raym...