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» Genes, Themes, and Microarrays: Using Information Retrieval ...
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BMCBI
2006
163views more  BMCBI 2006»
13 years 7 months ago
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological featur
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
J. R. Semeiks, A. Rizki, Mina J. Bissell, I. Saira...
BMCBI
2008
93views more  BMCBI 2008»
13 years 7 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2005
102views more  BMCBI 2005»
13 years 7 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
BMCBI
2007
146views more  BMCBI 2007»
13 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...