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EUROSYS
2006
ACM
14 years 5 months ago
On the road to recovery: restoring data after disasters
—Restoring data operations after a disaster is a daunting task: how should recovery be performed to minimize data loss and application downtime? Administrators are under consider...
Kimberly Keeton, Dirk Beyer 0002, Ernesto Brau, Ar...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
14 years 2 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
FM
2009
Springer
138views Formal Methods» more  FM 2009»
14 years 2 months ago
What Can Formal Methods Bring to Systems Biology?
This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...
GECCO
2009
Springer
14 years 2 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
CLADE
2008
IEEE
14 years 2 months ago
SWARM: a scientific workflow for supporting bayesian approaches to improve metabolic models
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Xinghua Shi, Rick Stevens