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BMCBI
2006
134views more  BMCBI 2006»
13 years 11 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
14 years 5 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...
BMCBI
2008
88views more  BMCBI 2008»
13 years 11 months ago
Large-scale identification of polymorphic microsatellites using an in silico approach
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
Jifeng Tang, Samantha J. Baldwin, Jeanne M. E. Jac...
BMCBI
2007
156views more  BMCBI 2007»
13 years 11 months ago
Predictive modeling of plant messenger RNA polyadenylation sites
Background: One of the essential processing events during pre-mRNA maturation is the posttranscriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track pr...
Guoli Ji, Jianti Zheng, Yingjia Shen, Xiaohui Wu, ...