Background: Comparative genomics is the analysis and comparison of genomes from different species. This area of research is driven by the large number of sequenced genomes and hea...
Mohamed Ibrahim Abouelhoda, Stefan Kurtz, Enno Ohl...
The Drosophila species comparative genome database DroSpeGe (http://insects.eugenes.org/ DroSpeGe/) provides genome researchers with rapid, usable access to 12 new and old Drosoph...
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Chaining fragments is a crucial step in genome alignment. Existing chaining algorithms compute a maximum weighted chain with no overlaps allowed between adjacent fragments. In prac...
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...