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» Genome Annotation and Comparison System
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BMCBI
2006
92views more  BMCBI 2006»
13 years 9 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
ALMOB
2008
160views more  ALMOB 2008»
13 years 10 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
BMCBI
2007
108views more  BMCBI 2007»
13 years 10 months ago
Integrating sequence and structural biology with DAS
Background: The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequenc...
Andreas Prlic, Thomas A. Down, Eugene Kulesha, Rob...
BMCBI
2010
135views more  BMCBI 2010»
13 years 10 months ago
Integration and visualization of systems biology data in context of the genome
Background: High-density tiling arrays and new sequencing technologies are generating rapidly increasing volumes of transcriptome and protein-DNA interaction data. Visualization a...
J. Christopher Bare, Tie Koide, David J. Reiss, Da...
BMCBI
2005
92views more  BMCBI 2005»
13 years 9 months ago
FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Philippe Gouret, Vérane Vitiello, Nathalie ...