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» Genome Sequence Assembly: Algorithms and Issues
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BMCBI
2008
104views more  BMCBI 2008»
13 years 8 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
CSB
2005
IEEE
132views Bioinformatics» more  CSB 2005»
13 years 10 months ago
A Fast Shotgun Assembly Heuristic
Genome sequencing opened a new era in genetics allowing the study of genomes at the nucleotide level. However, the chosen method of sequencing produced large numbers of nucleotide...
Christopher Wilks, Sami Khuri
JACM
2002
94views more  JACM 2002»
13 years 8 months ago
The greedy path-merging algorithm for contig scaffolding
Given a collection of contigs and mate-pairs. The Contig Scaffolding Problem is to order and orientate the given contigs in a manner that is consistent with as many mate-pairs as p...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
CIBCB
2007
IEEE
14 years 2 months ago
Multiple Sequence Alignment using Fuzzy Logic
—DNA matching is a crucial step in sequence alignment. Since sequence alignment is an approximate matching process there is a need for good approximate algorithms. The process of...
Sara Nasser, Gregory Vert, Monica N. Nicolescu, Al...
RECOMB
2009
Springer
14 years 3 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...