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BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly
RECOMB
2011
Springer
12 years 10 months ago
Simultaneous Structural Variation Discovery in Multiple Paired-End Sequenced Genomes
Fereydoun Hormozdiari, Iman Hajirasouliha, Andrew ...
WABI
2009
Springer
156views Bioinformatics» more  WABI 2009»
14 years 2 months ago
Phylogenetic Comparative Assembly
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Peter Husemann, Jens Stoye
BMCBI
2010
81views more  BMCBI 2010»
13 years 7 months ago
Empirical Bayes Analysis of Sequencing-based Transcriptional Profiling without Replicates
Background: Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based tran...
Zhijin Wu, Bethany D. Jenkins, Tatiana A. Rynearso...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher