EcoCyc is an organism-specific Pathway/Genome Database that describes the metabolic and signaltransduction pathways of Escherichia coli, its enzymes, and--a new addition--its tran...
Peter D. Karp, Monica Riley, Milton H. Saier Jr., ...
Background: The integration of genomic information with quantitative experimental data is a key component of systems biology. An increasing number of microbial genomes are being s...
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...