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CIKM
2008
Springer
13 years 9 months ago
A new method for indexing genomes using on-disk suffix trees
We propose a new method to build persistent suffix trees for indexing the genomic data. Our algorithm DiGeST (Disk-Based Genomic Suffix Tree) improves significantly over previous ...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
BMCBI
2007
167views more  BMCBI 2007»
13 years 7 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
GCB
2010
Springer
122views Biometrics» more  GCB 2010»
13 years 5 months ago
Quantitative Comparison of Genomic-Wide Protein Domain Distributions
Abstract: Investigations into the origins and evolution of regulatory mechanisms require quantitative estimates of the abundance and co-occurrence of functional protein domains amo...
Arli A. Parikesit, Peter F. Stadler, Sonja J. Proh...
SP
2008
IEEE
100views Security Privacy» more  SP 2008»
14 years 1 months ago
Towards Practical Privacy for Genomic Computation
Many basic tasks in computational biology involve operations on individual DNA and protein sequences. These sequences, even when anonymized, are vulnerable to re-identification a...
Somesh Jha, Louis Kruger, Vitaly Shmatikov
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
Finding genomic ontology terms in text using evidence content
Background: The development of text mining systems that annotate biological entities with their properties using scientific literature is an important recent research topic. These...
Francisco M. Couto, Mário J. Silva, Pedro C...