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BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
DATAMINE
2006
139views more  DATAMINE 2006»
13 years 8 months ago
VizRank: Data Visualization Guided by Machine Learning
Data visualization plays a crucial role in identifying interesting patterns in exploratory data analysis. Its use is, however, made difficult by the large number of possible data p...
Gregor Leban, Blaz Zupan, Gaj Vidmar, Ivan Bratko
NAR
2007
149views more  NAR 2007»
13 years 8 months ago
UniHI: an entry gate to the human protein interactome
Systematic mapping of protein–protein interactions has become a central task of functional genomics. To map the human interactome, several strategies have recently been pursued....
Gautam Chaurasia, Yasir Iqbal, Christian Häni...
NAR
2011
205views Computer Vision» more  NAR 2011»
12 years 11 months ago
The BRENDA Tissue Ontology (BTO): the first all-integrating ontology of all organisms for enzyme sources
BTO, the BRENDA Tissue Ontology (http://www .BTO.brenda-enzymes.org) represents a comprehensive structured encyclopedia of tissue terms. The project started in 2003 to create a co...
Marion Gremse, Antje Chang, Ida Schomburg, Andreas...
BMCBI
2008
101views more  BMCBI 2008»
13 years 8 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...