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BMCBI
2002
126views more  BMCBI 2002»
13 years 8 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
IDA
2009
Springer
13 years 6 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
BMCBI
2006
133views more  BMCBI 2006»
13 years 8 months ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
BMCBI
2004
124views more  BMCBI 2004»
13 years 8 months ago
The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)
Background: DopaNet http://www.dopanet.org is a Systems Biology initiative that aims to investigate precisely and quantitatively all the aspects of neurotransmission in a specific...
Nicolas Le Novère, Marco Donizelli