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CPM
2004
Springer
108views Combinatorics» more  CPM 2004»
14 years 26 days ago
Quadratic Time Algorithms for Finding Common Intervals in Two and More Sequences
A popular approach in comparative genomics is to locate groups or clusters of orthologous genes in multiple genomes and to postulate functional association between the genes contai...
Thomas Schmidt, Jens Stoye
BMCBI
2005
73views more  BMCBI 2005»
13 years 7 months ago
An analysis of extensible modelling for functional genomics data
Background: Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a mechanism for allowing e...
Andrew R. Jones, Norman W. Paton
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Statistical inference of chromosomal homology based on gene colinearity and applications to Arabidopsis and rice
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
Xiyin Wang, Xiaoli Shi, Zhe Li, Qihui Zhu, Lei Kon...