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CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Gene Teams with Relaxed Proximity Constraint
Functionally related genes co-evolve, probably due to the strong selection pressure in evolution. Thus we expect that they are present in multiple genomes. Physical proximity amon...
Sun Kim, Jeong-Hyeon Choi, Jiong Yang
NCA
2007
IEEE
13 years 7 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
BMCBI
2007
145views more  BMCBI 2007»
13 years 7 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...
BMCBI
2007
183views more  BMCBI 2007»
13 years 7 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
RECOMB
2005
Springer
14 years 7 months ago
Stability of Rearrangement Measures in the Comparison of Genome Sequences
We present data-analytic and statistical tools for studying rates of rearrangement of whole genomes and to assess the stability of these methods with changes in the level of resol...
David Sankoff, Matthew Mazowita