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ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
FSTTCS
2003
Springer
14 years 22 days ago
Comparing Sequences with Segment Rearrangements
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Funda Ergün, S. Muthukrishnan, Süleyman ...
BMCBI
2008
171views more  BMCBI 2008»
13 years 7 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
BMCBI
2007
116views more  BMCBI 2007»
13 years 7 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
JBI
2006
13 years 7 months ago
Phylogenetics by likelihood: Evolutionary modeling as a tool for understanding the genome
Molecular evolutionary studies provide a means of investigating how cells function and how organisms adapt to their environment. The products of evolutionary studies provide medic...
Carolin Kosiol, Lee Bofkin, Simon Whelan