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BMCBI
2007
145views more  BMCBI 2007»
13 years 7 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
ICMLA
2007
13 years 9 months ago
Maximum Likelihood Quantization of Genomic Features Using Dynamic Programming
Dynamic programming is introduced to quantize a continuous random variable into a discrete random variable. Quantization is often useful before statistical analysis or reconstruct...
Mingzhou (Joe) Song, Robert M. Haralick, Sté...
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
TREC
2003
13 years 9 months ago
Knowledge-Based Access to the Bio-Medical Literature, Ontologically-Grounded Experiments for the TREC 2003 Genomics Track
The Tarragon Consulting team participated in the primary task of the TREC 2003 Genomics Track. We used a combination of knowledge-engineering and corpus analysis to construct sema...
Richard Tong, John Quackenbush, Mark Snuffin
BIBE
2007
IEEE
169views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Combining Semantics, Context, and Statistical Evidence in Genomics Literature Search
—We present an information retrieval model for combining evidence from concept-based semantics, term statistics, and context for improving search precision of genomics literature...
Jay Urbain, Nazli Goharian, Ophir Frieder