—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
Abstract-- The advance of high-throughput experimental technologies poses continuous challenges to computational data analysis in functional and comparative genomics studies. Gene ...
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...