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WOB
2003
129views Bioinformatics» more  WOB 2003»
13 years 10 months ago
Procsimo: uma Ferramenta de Procura de Similaridade entre Operons
In this work, we propose a software tool, called PROCSIMO, which aims the identification of similarities between operons in bacterial genomes. From a database which contains the ch...
Carlos Azevedo, Alexandre Plastino, Ana Tereza R. ...
BMCBI
2008
144views more  BMCBI 2008»
13 years 9 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
GECCO
1999
Springer
130views Optimization» more  GECCO 1999»
14 years 1 months ago
Heterochrony and Adaptation in Developing Neural Networks
This paper discusses the simulation results of a model of biological development for neural networks based on a regulatory genome. The model’s results are analyzed using the fra...
Angelo Cangelosi
ISMB
2007
13 years 11 months ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
RECOMB
2008
Springer
14 years 9 months ago
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
Jotun Hein, Rune B. Lyngsø, Yun S. Song