Procsimo: uma Ferramenta de Procura de Similaridade entre Operons

In this work, we propose a software tool, called PROCSIMO, which aims the identification of similarities between operons in bacterial genomes. From a database which contains the characteristics and functionalities of operons, the proposed tool can: (a) identify those operons stored in the database that are similar to an operon under investigation, and (b) identify new operons in a complete genome, comparing sets of genes from this genome to the operons in the database. In order to allow the development of PROCSIMO, it was also necessary in this work to establish a set of criteria used to determine the similarity between operons. Computational experiments were conducted to validate the functionality of the proposed tool. 1 Introdução Muitos genes em genoma bacterianos estão organizados em operons, que para os propósitos deste trabalho são definidos como um conjunto de genes que são transcritos em uma única molécula de mRNA. A identificação de genes que estão agrupados em oper...

• Type: Conference
• Year: 2003
• Where: WOB
• Authors: Carlos Azevedo, Alexandre Plastino, Ana Tereza R. Vasconcelos
• Keywords: Em Operons, Operons, Organizados Em Operons, WOB 2003, WOB 2008