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BMCBI
2008
218views more  BMCBI 2008»
13 years 9 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...
JIB
2006
220views more  JIB 2006»
13 years 8 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
BMCBI
2005
89views more  BMCBI 2005»
13 years 8 months ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
BMCBI
2007
146views more  BMCBI 2007»
13 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2007
194views more  BMCBI 2007»
13 years 9 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung