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NAR
2008
113views more  NAR 2008»
13 years 7 months ago
miRNAMap 2.0: genomic maps of microRNAs in metazoan genomes
MicroRNAs (miRNAs) are small non-coding RNA molecules that can negatively regulate gene expression and thus control numerous cellular mechanisms. This work develops a resource, mi...
Sheng-Da Hsu, Chia-Huei Chu, Ann-Ping Tsou, Shu-Je...
RECOMB
2003
Springer
14 years 7 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
BMCBI
2011
13 years 2 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
BMCBI
2007
176views more  BMCBI 2007»
13 years 7 months ago
Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
Markus Weniger, Julia C. Engelmann, Jörg Schu...
RECOMB
2010
Springer
13 years 5 months ago
An Approximation Algorithm for Computing a Parsimonious First Speciation in the Gene Duplication Model
We consider the following problem: given a forest of gene family trees on a set of genomes, find a first speciation which splits these genomes into two subsets and minimizes the ...
Aïda Ouangraoua, Krister M. Swenson, Cedric C...