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CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 2 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
BIOINFORMATICS
2005
169views more  BIOINFORMATICS 2005»
13 years 8 months ago
A statistical model providing comprehensive predictions for the mRNA differential display
s Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22 is part of a protein folding helper complex in the ER [oral presentation] Manuela Heiner A carbamate-cleaving catalytic antibo...
David Meintrup, Ellen Reisinger
BMCBI
2007
131views more  BMCBI 2007»
13 years 8 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
BICOB
2009
Springer
14 years 3 months ago
A Bayesian Approach to High-Throughput Biological Model Generation
Abstract. With the availability of hundreds and soon-to-be thousands of complete genomes, the construction of genome-scale metabolic models for these organisms has attracted much a...
Xinghua Shi, Rick L. Stevens
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...