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BMCBI
2004
229views more  BMCBI 2004»
13 years 8 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
CEC
2007
IEEE
14 years 3 months ago
Achieving environmental tolerance through the initiation and exploitation of external information
— It is often believed that biological organisms have an inherent tolerance to environmental changes. This is a seductive concept if transferred to artificial organisms. An expe...
Gunnar Tufte, Pauline C. Haddow
ECAL
2005
Springer
14 years 2 months ago
CelloS: A Multi-level Approach to Evolutionary Dynamics
We study the evolution of simple cells that are equipped with a genome, a rudimentary gene regulation network at transcription level and two classes of functional genes: motion e...
Camille Stephan-Otto Attolini, Peter F. Stadler, C...
ALIFE
2008
13 years 8 months ago
Hierarchical Self-Organization in the Finitary Process Soup
Current analyses of genomes from numerous species show that the diversity of organism's functional and behavioral characters is not proportional to the number of genes that e...
Olof Görnerup, James P. Crutchfield