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BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
Quality control for terms and definitions in ontologies and taxonomies
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
Jacob Köhler, Katherine Munn, Alexander R&uum...
BMCBI
2005
132views more  BMCBI 2005»
13 years 8 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...
TAPIA
2009
ACM
14 years 3 months ago
A platform-based design environment for synthetic biological systems
Genomics has reached the stage at which the amount of DNA sequence information in existing databases is quite large. Synthetic biology is now using these databases to catalog sequ...
Douglas Densmore, Anne Van Devender, Matthew Johns...
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
13 years 8 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey