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BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2007
133views more  BMCBI 2007»
13 years 7 months ago
MATLIGN: a motif clustering, comparison and matching tool
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
Matti Kankainen, Ari Löytynoja
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
A Web-based and Grid-enabled dChip version for the analysis of large sets of gene expression data
Background: Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible f...
Luca Corradi, Marco Fato, Ivan Porro, Silvia Scagl...