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BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2007
119views more  BMCBI 2007»
13 years 7 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2007
101views more  BMCBI 2007»
13 years 7 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BIOINFORMATICS
2005
110views more  BIOINFORMATICS 2005»
13 years 7 months ago
Classification of oligonucleotide fingerprints: application for microbial community and gene expression analyses
Oligonucleotide fingerprinting is an array-based approach used for analysis of microbial community composition and gene expression profiling. Oligonucleotide fingerprinting of rib...
Katechan Jampachaisri, Lea Valinsky, James Bornema...