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139
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SDM
2004
SIAM
211views Data Mining» more  SDM 2004»
15 years 5 months ago
Using Support Vector Machines for Classifying Large Sets of Multi-Represented Objects
Databases are a key technology for molecular biology which is a very data intensive discipline. Since molecular biological databases are rather heterogeneous, unification and data...
Hans-Peter Kriegel, Peer Kröger, Alexey Pryak...
139
Voted
BMCBI
2010
98views more  BMCBI 2010»
15 years 3 months ago
Prediction of protein structural classes for low-homology sequences based on predicted secondary structure
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
Jian-Yi Yang, Zhen-Ling Peng, Xin Chen
140
Voted
BMCBI
2010
114views more  BMCBI 2010»
15 years 3 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
134
Voted
BMCBI
2007
146views more  BMCBI 2007»
15 years 3 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
159
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 3 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...