105 search results - page 6 / 21 » Graph-Kernels for the Comparative Analysis of Protein Active... |
BMCBI
2008
13 years 7 months ago
2008
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
BMCBI
2007
13 years 7 months ago
2007
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
BMCBI
2004
13 years 7 months ago
2004
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
BMCBI
2010
13 years 7 months ago
2010
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
BMCBI
2004
13 years 7 months ago
2004
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...