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» Haplotypes versus Genotypes on Pedigrees
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WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
BMCBI
2007
153views more  BMCBI 2007»
13 years 7 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
ICCS
2005
Springer
14 years 29 days ago
Phasing and Missing Data Recovery in Family Trios
Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is a...
Dumitru Brinza, Jingwu He, Weidong Mao, Alexander ...
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp