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» Hedging predictions in machine learning
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BMCBI
2010
125views more  BMCBI 2010»
15 years 4 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2007
141views more  BMCBI 2007»
15 years 4 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
BMCBI
2006
92views more  BMCBI 2006»
15 years 4 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
AIME
2009
Springer
15 years 9 months ago
Prediction of Mechanical Lung Parameters Using Gaussian Process Models
Abstract. Mechanical ventilation can cause severe lung damage by inadequate adjustment of the ventilator. We introduce a Machine Learning approach to predict the pressure-dependent...
Steven Ganzert, Stefan Kramer, Knut Möller, D...
BMCBI
2006
159views more  BMCBI 2006»
15 years 4 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey