46 search results - page 2 / 10 » Hidden Markov models for detecting remote protein homologies |
BMCBI
2007
13 years 7 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2006
13 years 7 months ago
2006
Background: The accuracy of protein secondary structure prediction has been improving steadily towards the 88% estimated theoretical limit. There are two types of prediction algor...
BMCBI
2011
13 years 2 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
JCB
1998
13 years 6 months ago
1998
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
BMCBI
2008
13 years 7 months ago
2008
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...