— Analysis of conformational changes is one of the keys to the understanding of protein functions and interactions. For the analysis, we often compare two protein structures, tak...
Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
Hidden Markov Models, or HMMs for short, have been recently used in Bioinformatics for the classification of DNA or protein chains, giving rise to what is known as Profile Hidde...
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...