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» Hidden conformations in protein structures
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CCE
2011
13 years 2 months ago
Computational energy-based redesign of robust proteins
The robustness of a system is a property that pervades all aspects of Nature. The ability of a system to adapt itself to perturbations due to internal and external agents, to agin...
Giovanni Stracquadanio, Giuseppe Nicosia
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski
BIOINFORMATICS
2011
12 years 11 months ago
ProDy: Protein Dynamics Inferred from Theory and Experiments
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
Ahmet Bakan, Lidio M. Meireles, Ivet Bahar