Sciweavers

176 search results - page 28 / 36
» Hidden conformations in protein structures
Sort
View
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
JCC
2002
80views more  JCC 2002»
13 years 7 months ago
Consistent treatment of inter- and intramolecular polarization in molecular mechanics calculations
: A protocol is described for the treatment of molecular polarization in force field calculations. The resulting model is consistent in that both inter- and intramolecular polariza...
Pengyu Ren, Jay W. Ponder
BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
NAR
2006
119views more  NAR 2006»
13 years 7 months ago
HHsenser: exhaustive transitive profile search using HMM-HMM comparison
HHsenser is the first server to offer exhaustive intermediate profile searches, which it combines with pairwise comparison of hidden Markov models. Starting from a single protein ...
Johannes Söding, Michael Remmert, Andreas Bie...
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone