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BMCBI
2010
144views more  BMCBI 2010»
13 years 9 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2010
117views more  BMCBI 2010»
13 years 9 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
BMCBI
2007
166views more  BMCBI 2007»
13 years 9 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
ML
2008
ACM
101views Machine Learning» more  ML 2008»
13 years 9 months ago
On reoptimizing multi-class classifiers
Significant changes in the instance distribution or associated cost function of a learning problem require one to reoptimize a previously-learned classifier to work under new cond...
Chris Bourke, Kun Deng, Stephen D. Scott, Robert E...
TCBB
2008
115views more  TCBB 2008»
13 years 9 months ago
Highly Scalable Genotype Phasing by Entropy Minimization
A Single Nucleotide Polymorphism (SNP) is a position in the genome at which two or more of the possible four nucleotides occur in a large percentage of the population. SNPs accoun...
Alexander Gusev, Ion I. Mandoiu, Bogdan Pasaniuc