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BMCBI
2008
99views more  BMCBI 2008»
13 years 9 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2007
110views more  BMCBI 2007»
13 years 9 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...
MST
2006
149views more  MST 2006»
13 years 9 months ago
Parameterized Intractability of Distinguishing Substring Selection
A central question in computational biology is the design of genetic markers to distinguish between two given sets of (DNA) sequences. This question is formalized as the NP-comple...
Jens Gramm, Jiong Guo, Rolf Niedermeier
SP
2008
IEEE
134views Security Privacy» more  SP 2008»
13 years 9 months ago
Discover gene specific local co-regulations from time-course gene expression data
Discovering gene co-regulatory relationships is one of most important research in DNA microarray data analysis. The problem of gene specific co-regulation discovery is to, for a p...
Ji Zhang, Qigang Gao, Hai H. Wang
BMCBI
2005
84views more  BMCBI 2005»
13 years 9 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...