Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
Markus Seiler, Alexander Mehrle, Annemarie Poustka...
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
Background: Protein interactions support cell organization and mediate its response to any specific stimulus. Recent technological advances have produced large data-sets that aim ...