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BMCBI
2010
146views more  BMCBI 2010»
13 years 9 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
BMCBI
2010
124views more  BMCBI 2010»
13 years 9 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2007
153views more  BMCBI 2007»
13 years 9 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
BMCBI
2007
94views more  BMCBI 2007»
13 years 9 months ago
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
ARTMED
2006
158views more  ARTMED 2006»
13 years 9 months ago
CareVis: Integrated visualization of computerized protocols and temporal patient data
Objective: Currently, visualization support for patient data analysis is mostly limited to the representation of directly measured data. Contextual information on performed treatm...
Wolfgang Aigner, Silvia Miksch