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BMCBI
2011
13 years 2 months ago
PheMaDB: A solution for storage, retrieval, and analysis of high throughput phenotype data
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
Wenling E. Chang, Keri Sarver, Brandon W. Higgs, T...
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2011
13 years 2 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...