392 search results - page 18 / 79 » High-Precision Function Prediction using Conserved Interacti... |
BMCBI
2008
13 years 8 months ago
2008
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
BIBM
2008
IEEE
14 years 3 months ago
2008
IEEE
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
BIBE
2005
IEEE
14 years 2 months ago
2005
IEEE
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
BMCBI
2007
13 years 8 months ago
2007
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
BMCBI
2007
13 years 8 months ago
2007
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...