392 search results - page 4 / 79 » High-Precision Function Prediction using Conserved Interacti... |
BMCBI
2008
13 years 8 months ago
2008
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
BMCBI
2010
13 years 3 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
BMCBI
2007
13 years 8 months ago
2007
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
BMCBI
2005
13 years 8 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
BMCBI
2007
13 years 8 months ago
2007
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...