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WADT
1998
Springer
14 years 2 months ago
Hierarchical Heterogeneous Specifications
We propose a definition of hierarchical heterogeneous formal specifications, where each module is specified according to its own homogeneous logic. We focus on the specification st...
Sophie Coudert, Gilles Bernot, Pascale Le Gall
CIKM
2005
Springer
14 years 3 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
BMCBI
2010
153views more  BMCBI 2010»
13 years 10 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2002
76views more  BMCBI 2002»
13 years 9 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman
BMCBI
2010
129views more  BMCBI 2010»
13 years 10 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas