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» Homologous Crossover in Genetic Programming
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BMCBI
2005
119views more  BMCBI 2005»
13 years 6 months ago
GASH: An improved algorithm for maximizing the number of equivalent residues between two protein structures
Background: We introduce GASH, a new, publicly accessible program for structural alignment and superposition. Alignments are scored by the Number of Equivalent Residues (NER), a q...
Daron M. Standley, Hiroyuki Toh, Haruki Nakamura
BMCBI
2006
115views more  BMCBI 2006»
13 years 6 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
CCS
2009
ACM
14 years 1 months ago
Privacy-preserving genomic computation through program specialization
In this paper, we present a new approach to performing important classes of genomic computations (e.g., search for homologous genes) that makes a significant step towards privacy...
Rui Wang, XiaoFeng Wang, Zhou Li, Haixu Tang, Mich...
BMCBI
2002
109views more  BMCBI 2002»
13 years 6 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
BMCBI
2008
135views more  BMCBI 2008»
13 years 6 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...