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NAR
2006
84views more  NAR 2006»
13 years 8 months ago
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
Jeffrey G. Mandell, Carlos F. Barbas III
BMCBI
2005
114views more  BMCBI 2005»
13 years 8 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
TEC
2002
117views more  TEC 2002»
13 years 8 months ago
A genetic algorithm for shortest path routing problem and the sizing of populations
This paper presents a genetic algorithmic approach to the shortest path (SP) routing problem. Variable-length chromosomes (strings) and their genes (parameters) have been used for ...
Chang Wook Ahn, Rudrapatna S. Ramakrishna
SCFBM
2008
87views more  SCFBM 2008»
13 years 8 months ago
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....
CIKM
2010
Springer
13 years 7 months ago
Reverted indexing for feedback and expansion
Traditional interactive information retrieval systems function by creating inverted lists, or term indexes. For every term in the vocabulary, a list is created that contains the d...
Jeremy Pickens, Matthew Cooper, Gene Golovchinsky