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JCB
2008
170views more  JCB 2008»
13 years 7 months ago
Efficiently Identifying Max-Gap Clusters in Pairwise Genome Comparison
The spatial clustering of genes across different genomes has been used to study important problems in comparative genomics, from identification of operons to detection of homologo...
Xu Ling, Xin He, Dong Xin, Jiawei Han
SBACPAD
2003
IEEE
120views Hardware» more  SBACPAD 2003»
14 years 23 days ago
Comparison of Genomes Using High-Performance Parallel Computing
Comparison of the DNA sequences and genes of two genomes can be useful to investigate the common functionalities of the corresponding organisms and get a better understanding of h...
Nalvo F. Almeida Jr., Carlos E. R. Alves, Edson C&...
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2006
143views more  BMCBI 2006»
13 years 7 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
CEC
2005
IEEE
14 years 1 months ago
Geometric landscape of homologous crossover for syntactic trees
The relationship between search space, distances and genetic operators for syntactic trees is little understood. Geometric crossover and geometric mutation are representation-indep...
Alberto Moraglio, Riccardo Poli