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BMCBI
2005
84views more  BMCBI 2005»
13 years 7 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
BMCBI
2008
113views more  BMCBI 2008»
13 years 7 months ago
SynBlast: Assisting the analysis of conserved synteny information
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
Jörg Lehmann, Peter F. Stadler, Sonja J. Proh...
NAR
2011
188views Computer Vision» more  NAR 2011»
12 years 10 months ago
The Gene Expression Barcode: leveraging public data repositories to begin cataloging the human and murine transcriptomes
Various databases have harnessed the wealth of publicly available microarray data to address biological questions ranging from across-tissue differential expression to homologous ...
Matthew N. McCall, Karan Uppal, Harris A. Jaffee, ...
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...
CSB
2005
IEEE
182views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Bacterial Whole Genome Phylogeny Using Proteome Comparison and Optimal Reversal Distance
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
Noppadon Khiripet