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BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
Discrete profile comparison using information bottleneck
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
DWARF - a data warehouse system for analyzing protein families
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
GECCO
2005
Springer
131views Optimization» more  GECCO 2005»
14 years 1 months ago
Multipopulation cooperative coevolutionary programming (MCCP) to enhance design innovation
This paper describes the development of an evolutionary algorithm called Multipopulation Cooperative Coevolutionary Programming (MCCP) that extends Genetic Programming (GP) to sea...
Emily M. Zechman, S. Ranji Ranjithan
ICASSP
2007
IEEE
14 years 2 months ago
Fast Search of Sequences with Complex Symbol Correlations using Profile Context-Sensitive HMMS and Pre-Screening Filters
Recently, profile context-sensitive HMMs (profile-csHMMs) have been proposed which are very effective in modeling the common patterns and motifs in related symbol sequences. Pro...
Byung-Jun Yoon, P. P. Vaidyanathan