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ECAI
2004
Springer
14 years 13 days ago
Avoiding Data Overfitting in Scientific Discovery: Experiments in Functional Genomics
Functional genomics is a typical scientific discovery domain characterized by a very large number of attributes (genes) relative to the number of examples (observations). The dang...
Dragan Gamberger, Nada Lavrac
EWC
2000
105views more  EWC 2000»
13 years 8 months ago
Design Families and Design Individuals
: This paper discusses design families and design individuals. Phase space is introduced to complement state space. Phase transition as a generic method of generating design famili...
Xiao-Guang Shi, John S. Gero
BMCBI
2010
167views more  BMCBI 2010»
13 years 8 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
ICALP
2001
Springer
14 years 1 months ago
Permutation Editing and Matching via Embeddings
Abstract. If the genetic maps of two species are modelled as permutations of (homologous) genes, the number of chromosomal rearrangements in the form of deletions, block moves, inv...
Graham Cormode, S. Muthukrishnan, Süleyman Ce...
BMCBI
2008
131views more  BMCBI 2008»
13 years 8 months ago
Major copy proportion analysis of tumor samples using SNP arrays
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
Cheng Li, Rameen Beroukhim, Barbara A. Weir, Wendy...